Oral mucocele is a common lesion of the oral mucosa that results from an alteration of minor salivary glands due to mucous accumulation<\/p>\n\n\n\n
Table of Contents<\/p>\nToggle<\/span><\/path><\/svg><\/svg><\/span><\/span><\/label>General features of Oral Mucocele:<\/a><\/li>Epidemiology:<\/a><\/li>Oral Mucocele Clinical features:<\/a><\/li>Pathogenesis of Oral Mucocele:<\/a>Extravasation mucocele:<\/a><\/li>Retention mucocele:<\/a><\/li><\/ul><\/li>Histopathology:<\/a><\/li>Oral Mucocele Treatment:<\/a><\/li>Medinaz Dental Cyst Book<\/a><\/li><\/ul><\/nav><\/div>\n<\/span>General features of Oral Mucocele<\/mark>:<\/span><\/h2>\n\n\n\nOral Mucocele is a common lesion<\/em><\/strong> of the oral mucosa that results from an alteration of minor salivary glands due to mucous accumulation.<\/li>Other tissues<\/em><\/strong> where mucocele may be seen:Appendix, Gall bladder, Paranasal sinuses and Lacrimal sac. <\/li>Mucocele involves mucin accumulation<\/em><\/strong> in connective tissue and swelling <\/li>Two types<\/em><\/strong> of mucocele – extravasation and retention. <\/li>There is no epithelial lining<\/em><\/strong>. <\/li>Extravasation mucocele<\/em><\/strong>: due to broken salivary gland ducts <\/strong>and consequent spillage into the soft tissues around this gland. <\/li>Retention mucocele<\/em><\/strong>: due to a decrease or absence of glandular secretion produced by blockage of the salivary gland ducts. <\/em><\/strong><\/li>When located on the floor of the mouth these lesions are called ranulas<\/em><\/strong> because the inflammation resembles the cheeks of a frog: – Usually associated with sub-lingual salivary gland<\/em><\/strong>. <\/li><\/ul>\n\n\n\nOral mucocele Types<\/figcaption><\/figure>\n\n\n\n<\/span>Epidemiology:<\/span><\/h2>\n\n\n\nFrequency: Common lesion<\/em><\/strong> <\/li>Extravasation<\/em><\/strong> more common than retention cyst. <\/li>Age: more common in children<\/em><\/strong> and young adults<\/em><\/strong>; with highest frequency in 2nd decade. <\/li>Gender<\/em><\/strong>: no gender predilection. <\/li>Site: mucocele can appear at any site of the oral mucosa containing <\/li>salivary glands. <\/li>Most common on lower lip<\/em><\/strong>; followed by floor of mouth & ventral tongue > Palate > Buccal mucosa > upper lip; and least common in retromolar pad and posterior dorsal area of the tongue. <\/li><\/ul>\n\n\n\n<\/span>Oral Mucocele Clinical features:<\/span><\/h2>\n\n\n\nPatients usually complain of a painless swelling<\/em><\/strong> which is frequently recurrent. <\/li>Mucoceles can appear at anywhere in the oral mucosa such as lip, cheeks and the floor of the mouth, but mainly appear in the lip. (Ref<\/a>)<\/li>Duration of lesion<\/em><\/strong> may be from few days to months or even years as patients might not seek treatment immediately. <\/li>Swelling may develop suddenly at meal times and many drain spontaneously at intervals. <\/li>Superficial mucocoele<\/em><\/strong> may be only 1\u20132mm in diameter but deeper mucocele<\/em><\/strong> is usually larger, the majority being between 5 and 10mm in diameter. <\/li>The swellings are round<\/em><\/strong> or oval<\/em><\/strong> and smooth<\/em><\/strong>.<\/li>Superficial Mucoceles present a bluish, soft and transparent cystic swelling which frequently resolves spontaneously.<\/li>Deeper lesions are the colour of normal mucosa and are firmer.<\/li>Mucoceles associated with the glands of Blandin and Nuhn<\/em><\/strong> on the anterior ventralaspect of the tongue are usually less than 10mm in diameter, and usually appear as polypoid or pedunculated swellings: may interfere with normal feeding or breathing.<\/li><\/ul>\n\n\n\n<\/span>Pathogenesis of Oral Mucocele:<\/span><\/h2>\n\n\n\nTwo etiological factors<\/em><\/strong> in mucoceles: trauma<\/em><\/strong> and obstruction<\/em><\/strong> of salivary gland ducts<\/p>\n\n\n\n<\/span>Extravasation mucocele:<\/span><\/h3>\n\n\n\nExtravasation mucoceles are caused by a leaking of fluid<\/em><\/strong> from surrounding tissue ducts or acini.<\/li>Extravasation mucocele is commonly found on the minor salivary glands<\/em><\/strong>. <\/li>Physical trauma<\/em><\/strong> can cause a leakage of salivary secretion into surrounding submucosal tissue, stagnant mucous leads to Inflammation<\/em><\/strong>.<\/li><\/ul>\n\n\n\nMucocele Extravasation Type<\/figcaption><\/figure>\n\n\n\nExtravasation mucoceles undergo three evolutionary phases<\/em><\/strong>.<\/li><\/ul>\n\n\n\nFirst phase: mucous spills<\/em><\/strong> diffusely from the excretory duct into conjunctive tissues where some leucocytes and histiocytes are found.<\/li>Second Phase: Granulomas<\/em><\/strong> appear during the resorption phase due to histocytes, macrophages and giant multinucleated cells associated with a foreign body reaction<\/em><\/strong>.<\/li>Third phase<\/em><\/strong>: Connective cells form a pseudocapsule<\/strong> without epithelium around the mucosa.<\/li><\/ol>\n\n\n\n<\/span>Retention mucocele:<\/span><\/h3>\n\n\n\nOral Mucocele Retention Type<\/figcaption><\/figure>\n\n\n\nRetention mucoceles are formed by dilation of the duct<\/em><\/strong> secondary to its obstruction or caused by a sialolith or dense mucosa<\/em><\/strong>. <\/li>Majority of retention cysts are associated with major salivary glands<\/em><\/strong>. <\/li><\/ul>\n\n\n\nMucocele mnemonic Extravasation vs Retention<\/figcaption><\/figure>\n\n\n\n<\/span>Histopathology:<\/span><\/h2>\n\n\n\nRobinson and Hj\u00f8rting-Hansen<\/em><\/strong> in 1964 described three distinct morphological patterns<\/em><\/strong> of mucocoele microscopically.<\/li><\/ul>\n\n\n\nThe first two represent mucous extravasation<\/em><\/strong> cysts and<\/li>Third mucous retention<\/em><\/strong> cysts.<\/li><\/ol>\n\n\n\nThe cyst contains faintly eosinophilic mucinous material<\/em><\/strong> and numerous vacuolated macrophages which are often called \u2018muciphages<\/em><\/strong>\u2019. <\/li>The mucinous material is surrounded by granulation tissue, or dense fibrous tissue<\/em><\/strong> or both<\/em><\/strong>. <\/li>The fibrous tissue is infiltrated by vacuolated macrophages, lymphocytes<\/em><\/strong> and polymorphonuclear leucocytes<\/em><\/strong>, including eosinophils<\/em><\/strong>. <\/li>In some cases, a ruptured salivary duct<\/em><\/strong> may be identified feeding into the mucinous area. One or more dilated ducts may be present <\/li>Occasionally, mucocele may show epithelial lining, which possibly represents a portion of excretory duct. <\/li>Epithelial lining<\/em><\/strong> may also be seen in case of a retention cyst. <\/li>The associated salivary gland, acini<\/em><\/strong> which often show alterations: <\/li><\/ul>\n\n\n\nMay consist of interstitial inflammation or sialadenitis<\/em><\/strong>,<\/li>Dilatation<\/em><\/strong> of intralobular and interlobular ducts with collection of mucus, and<\/li>Breakdown of individual acinar mucous cells resulting in the formation of tiny areas of pooled mucus<\/em><\/strong><\/li><\/ol>\n\n\n\nMucocele Histopathology image<\/figcaption><\/figure>\n\n\n\n<\/span>Oral Mucocele Treatment:<\/span><\/h2>\n\n\n\nConventional treatment is surgical extirpation<\/em><\/strong> of the surrounding mucosa and glandular tissue down to the muscle layer.<\/li>Some mucoceles are short-lived lesions that rupture and heal by themselves<\/em><\/strong>. <\/li>In the case of larger mucoceles, marsupialization<\/em><\/strong> may be done to avoid damage to vital structures. <\/li>Whenever possible the associated lobules of salivary gland should be removed with the cyst intact. <\/li><\/ul>\n\n\n\n<\/span>Medinaz Dental Cyst Book<\/span><\/h2>\n\n\n\nMedinaz Dental Cyst Book<\/figcaption><\/figure>\n\n\n\n“High Yield Visual Book of Dental Cyst” is now available on “Medinaz” App. The App is available on Appstore & Playstore. Visit our website www.medinaz.com<\/a> for other available books.<\/p>\n\n\n\nBook overview:<\/strong>– All the necessary High-Yield Points<\/strong>– 230+ Frequently tested facts<\/strong>
Two etiological factors<\/em><\/strong> in mucoceles: trauma<\/em><\/strong> and obstruction<\/em><\/strong> of salivary gland ducts<\/p>\n\n\n\n<\/span>Extravasation mucocele:<\/span><\/h3>\n\n\n\nExtravasation mucoceles are caused by a leaking of fluid<\/em><\/strong> from surrounding tissue ducts or acini.<\/li>Extravasation mucocele is commonly found on the minor salivary glands<\/em><\/strong>. <\/li>Physical trauma<\/em><\/strong> can cause a leakage of salivary secretion into surrounding submucosal tissue, stagnant mucous leads to Inflammation<\/em><\/strong>.<\/li><\/ul>\n\n\n\nMucocele Extravasation Type<\/figcaption><\/figure>\n\n\n\nExtravasation mucoceles undergo three evolutionary phases<\/em><\/strong>.<\/li><\/ul>\n\n\n\nFirst phase: mucous spills<\/em><\/strong> diffusely from the excretory duct into conjunctive tissues where some leucocytes and histiocytes are found.<\/li>Second Phase: Granulomas<\/em><\/strong> appear during the resorption phase due to histocytes, macrophages and giant multinucleated cells associated with a foreign body reaction<\/em><\/strong>.<\/li>Third phase<\/em><\/strong>: Connective cells form a pseudocapsule<\/strong> without epithelium around the mucosa.<\/li><\/ol>\n\n\n\n<\/span>Retention mucocele:<\/span><\/h3>\n\n\n\nOral Mucocele Retention Type<\/figcaption><\/figure>\n\n\n\nRetention mucoceles are formed by dilation of the duct<\/em><\/strong> secondary to its obstruction or caused by a sialolith or dense mucosa<\/em><\/strong>. <\/li>Majority of retention cysts are associated with major salivary glands<\/em><\/strong>. <\/li><\/ul>\n\n\n\nMucocele mnemonic Extravasation vs Retention<\/figcaption><\/figure>\n\n\n\n<\/span>Histopathology:<\/span><\/h2>\n\n\n\nRobinson and Hj\u00f8rting-Hansen<\/em><\/strong> in 1964 described three distinct morphological patterns<\/em><\/strong> of mucocoele microscopically.<\/li><\/ul>\n\n\n\nThe first two represent mucous extravasation<\/em><\/strong> cysts and<\/li>Third mucous retention<\/em><\/strong> cysts.<\/li><\/ol>\n\n\n\nThe cyst contains faintly eosinophilic mucinous material<\/em><\/strong> and numerous vacuolated macrophages which are often called \u2018muciphages<\/em><\/strong>\u2019. <\/li>The mucinous material is surrounded by granulation tissue, or dense fibrous tissue<\/em><\/strong> or both<\/em><\/strong>. <\/li>The fibrous tissue is infiltrated by vacuolated macrophages, lymphocytes<\/em><\/strong> and polymorphonuclear leucocytes<\/em><\/strong>, including eosinophils<\/em><\/strong>. <\/li>In some cases, a ruptured salivary duct<\/em><\/strong> may be identified feeding into the mucinous area. One or more dilated ducts may be present <\/li>Occasionally, mucocele may show epithelial lining, which possibly represents a portion of excretory duct. <\/li>Epithelial lining<\/em><\/strong> may also be seen in case of a retention cyst. <\/li>The associated salivary gland, acini<\/em><\/strong> which often show alterations: <\/li><\/ul>\n\n\n\nMay consist of interstitial inflammation or sialadenitis<\/em><\/strong>,<\/li>Dilatation<\/em><\/strong> of intralobular and interlobular ducts with collection of mucus, and<\/li>Breakdown of individual acinar mucous cells resulting in the formation of tiny areas of pooled mucus<\/em><\/strong><\/li><\/ol>\n\n\n\nMucocele Histopathology image<\/figcaption><\/figure>\n\n\n\n<\/span>Oral Mucocele Treatment:<\/span><\/h2>\n\n\n\nConventional treatment is surgical extirpation<\/em><\/strong> of the surrounding mucosa and glandular tissue down to the muscle layer.<\/li>Some mucoceles are short-lived lesions that rupture and heal by themselves<\/em><\/strong>. <\/li>In the case of larger mucoceles, marsupialization<\/em><\/strong> may be done to avoid damage to vital structures. <\/li>Whenever possible the associated lobules of salivary gland should be removed with the cyst intact. <\/li><\/ul>\n\n\n\n<\/span>Medinaz Dental Cyst Book<\/span><\/h2>\n\n\n\nMedinaz Dental Cyst Book<\/figcaption><\/figure>\n\n\n\n“High Yield Visual Book of Dental Cyst” is now available on “Medinaz” App. The App is available on Appstore & Playstore. Visit our website www.medinaz.com<\/a> for other available books.<\/p>\n\n\n\nBook overview:<\/strong>– All the necessary High-Yield Points<\/strong>– 230+ Frequently tested facts<\/strong>
“High Yield Visual Book of Dental Cyst” is now available on “Medinaz” App. The App is available on Appstore & Playstore. Visit our website www.medinaz.com<\/a> for other available books.<\/p>\n\n\n\nBook overview:<\/strong>– All the necessary High-Yield Points<\/strong>– 230+ Frequently tested facts<\/strong>
Book overview:<\/strong>– All the necessary High-Yield Points<\/strong>– 230+ Frequently tested facts<\/strong>