{"id":663,"date":"2022-06-16T08:11:33","date_gmt":"2022-06-16T08:11:33","guid":{"rendered":"https:\/\/medinaz.com\/blog\/?p=663"},"modified":"2022-06-16T08:11:34","modified_gmt":"2022-06-16T08:11:34","slug":"antifungal-medications-used-in-dentistry","status":"publish","type":"post","link":"https:\/\/medinaz.com\/blog\/2022\/06\/16\/antifungal-medications-used-in-dentistry\/","title":{"rendered":"Antifungal Medications Used in Dentistry"},"content":{"rendered":"\n<p>Here the Antifungal Medications Used in Dentistry with trade names, indications, dosage, side-effects &amp; drug interactions<\/p>\n\n\n\n<p class=\"has-text-align-center has-pale-cyan-blue-background-color has-background\"><strong>Nystatin\u00a0<\/strong><\/p>\n\n\n\n<p><strong>Trade Name:<\/strong><\/p>\n\n\n\n<p>Mycostatin pastilles<\/p>\n\n\n\n<p>Mycostatin oral suspension&nbsp;<\/p>\n\n\n\n<p><strong>Indications:<\/strong><\/p>\n\n\n\n<p>Oral candidiasis&nbsp;<\/p>\n\n\n\n<p><strong>Dosage:<\/strong><\/p>\n\n\n\n<p>One or two pastilles (200,000-400,000 units) dissolved slowly in the mouth 4 to 5 times daily for 10 to 14 days&nbsp;<\/p>\n\n\n\n<p><strong>Side effects\/Adverse Reactions:<\/strong><\/p>\n\n\n\n<p>This Antifungal medications can cause Nausea, diarrhea, vomiting with large doses\u00a0<\/p>\n\n\n\n<p><strong>Drug interactions<\/strong>:<\/p>\n\n\n\n<p>None known&nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center has-pale-pink-background-color has-background\"><strong>Clotrimazole\u00a0<\/strong><\/p>\n\n\n\n<p><strong>Trade Name<\/strong>:<\/p>\n\n\n\n<p>1. Mycelex oral troches<\/p>\n\n\n\n<p>2. Candid mouth paint&nbsp;<\/p>\n\n\n\n<p><strong>Indications<\/strong>:<\/p>\n\n\n\n<p>Oral candidiasis&nbsp;<\/p>\n\n\n\n<p><strong>Dosage<\/strong>:<\/p>\n\n\n\n<ol><li>Dissolve 1 troche (10 mg) slowly in the mouth, 5 times daily for 10 to 14 days&nbsp;<\/li><li>Apply topically 3-4 times a day<\/li><\/ol>\n\n\n\n<p><strong>Side effects\/Adverse Reactions<\/strong>:<\/p>\n\n\n\n<p>Mild elevations of liver enzymes in 15% of patients, Periodic assessment of liver function in patients with hepatic impairment, Nausea, vomiting&nbsp;<\/p>\n\n\n\n<p><strong>Drug interactions<\/strong>:<\/p>\n\n\n\n<p>No significant drug interactions&nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center has-light-green-cyan-background-color has-background\"><strong>Ketoconazole<\/strong> \u00a0<\/p>\n\n\n\n<p><strong>Trade Name<\/strong>:<\/p>\n\n\n\n<p>Nizoral tablets&nbsp;<\/p>\n\n\n\n<p><strong>Indications<\/strong>:<\/p>\n\n\n\n<p>1. Oral candidiasis, Blastomycosis,&nbsp;<\/p>\n\n\n\n<p>2. Coccidioidomycosis Histoplasmosis Paracoccidioidomycosis&nbsp;<\/p>\n\n\n\n<p><strong>Dosage<\/strong>:<\/p>\n\n\n\n<ol><li>Not to be used as initial therapy for oral candidiasis. One tablet (200 mg) daily for 1 to 2 weeks for candidiasis<\/li><li>Minimum treatment period for systemic mycoses is 6 months&nbsp;<\/li><\/ol>\n\n\n\n<p><strong>Side effects\/Adverse Reactions:<\/strong><\/p>\n\n\n\n<p>1. Serious hepatotoxicity in 1 : 10,000 patients<br>Monitoring of liver function is indicated for patients with preexisting hepatic problems, patients who develop symptoms of hepatic failure, or patients treated for more than 28 days&nbsp;<\/p>\n\n\n\n<p>2. Serum testosterone is lowered&nbsp;<\/p>\n\n\n\n<p>Nausea, vomiting<br>Anaphylaxis&nbsp;<\/p>\n\n\n\n<p><strong>Drug interactions<\/strong>:<\/p>\n\n\n\n<p>Serious and\/or life-threatening interactions with erythromycin. Metabolism of cyclosporine, tacrolimus, methylprednisolone, midazolam, triazolam, coumarin-like drugs, phenytoin, and rifampin may be altered&nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center has-pale-cyan-blue-background-color has-background\"><strong>Fluconazole\u00a0<\/strong><\/p>\n\n\n\n<p><strong>Trade Name<\/strong>:<\/p>\n\n\n\n<p>Diflucan tablets<\/p>\n\n\n\n<p><strong>Indications<\/strong>:<\/p>\n\n\n\n<p>Oral candidiasis, Cryptococcal meningitis&nbsp;<\/p>\n\n\n\n<p><strong>Dosage<\/strong>:<\/p>\n\n\n\n<p>For oral candidiasis: two tablets (200 mg) on day 1 and then one tablet (100 mg) daily for 1 to 2 weeks.<\/p>\n\n\n\n<p><strong>Side effects\/Adverse Reactions<\/strong>:<\/p>\n\n\n\n<p>Rare cases of hepatotoxicity, ranging from mild transient elevation of liver enzymes to hepatic failure, Headache, nausea, vomiting, abdominal pain, diarrhea&nbsp;<\/p>\n\n\n\n<p><strong>Drug interactions<\/strong>:<\/p>\n\n\n\n<p>Clinically or potentially significant side effects have been noted with the following medications: oral hypoglycemic agents, coumarin-like drugs, phenytoin, cyclosporine, rifampin, theophylline, rifabutin, and tacrolimus&nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center has-pale-pink-background-color has-background\"><strong>Itraconazole <\/strong>\u00a0<\/p>\n\n\n\n<p><strong>Trade Name<\/strong>:<\/p>\n\n\n\n<p>Sporanox capsules&nbsp;<\/p>\n\n\n\n<p><strong>Indications<\/strong>:<\/p>\n\n\n\n<p>1. Blastomycosis Histoplasmosis&nbsp;<\/p>\n\n\n\n<p>2. Aspergillosis refractory to amphotericin B therapy&nbsp;<\/p>\n\n\n\n<p><strong>Dosage<\/strong>:<\/p>\n\n\n\n<ol><li>For blastomycosis and histoplasmosis: two capsules (200 mg) daily, increasing by 100-mg increments up to 400 mg daily in divided doses if no clinical response is noted.<\/li><li>For aspergillosis: 200 to 400 mg daily&nbsp;<\/li><li>For life-threatening situations: loading dose of 200 mg t.i.d. for first 3 days, then dose can be reduced.&nbsp;<\/li><li>Treatment should continue for at least 3 months for all of the above&nbsp;<\/li><\/ol>\n\n\n\n<p><strong>Side effects\/Adverse Reactions<\/strong>:<\/p>\n\n\n\n<p>Rare cases of hepatoxicity&nbsp;<\/p>\n\n\n\n<p>Liver function should be monitored in patients with preexisting hepatic problems on therapy for more than 1 month&nbsp;<\/p>\n\n\n\n<p>Nausea, diarrhea, vomiting<\/p>\n\n\n\n<p><strong>Drug interactions<\/strong>:<\/p>\n\n\n\n<p>Serious and\/or life-threatening interactions with erythromycin, pimozide, quinidine, oral triazolam, and oral midazolam&nbsp;<\/p>\n\n\n\n<p>Lovastatin and simvastatin should be discontinued&nbsp;<\/p>\n\n\n\n<p>Increased plasma concentrations may be seen with warfarin, ritonavir, indinavir, vinca alkaloid agents, diazepam, cyclosporine, dihydropyridine medications, tacrolimus, digoxin, and methylprednisolone&nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center has-light-green-cyan-background-color has-background\"><strong>Itraconazole<\/strong>\u00a0<\/p>\n\n\n\n<p><strong>Trade Name<\/strong>:<\/p>\n\n\n\n<p>Sporanox oral solution&nbsp;<\/p>\n\n\n\n<p><strong>Indications<\/strong>:<\/p>\n\n\n\n<p>Oral candidiasis&nbsp;<\/p>\n\n\n\n<p><strong>Dosage<\/strong>:<\/p>\n\n\n\n<p>10 mL (100 mg) vigorously swished in the mouth and swallowed, twice daily for 1 to 2 weeks.<\/p>\n\n\n\n<p><strong>Side effects\/Adverse Reactions<\/strong>:<\/p>\n\n\n\n<p>This Antifungal medications can cases of hepatotoxicity but it is very rare.<\/p>\n\n\n\n<p>Liver function should be monitored in patients with preexisting hepatic problems on therapy for more than 1 month&nbsp;<\/p>\n\n\n\n<p>Nausea, diarrhea, vomiting&nbsp;<\/p>\n\n\n\n<p><strong>Drug interactions<\/strong>:<\/p>\n\n\n\n<p>Serious and\/or life-threatening interactions with erythromycin, oral triazolam, and oral midazolam,<\/p>\n\n\n\n<p>Lovastatin and simvastatin should be discontinued&nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center has-pale-cyan-blue-background-color has-background\"><strong>Amphotericin B<\/strong>\u00a0<\/p>\n\n\n\n<p><strong>Trade Name<\/strong>:<\/p>\n\n\n\n<p>Fungizone oral suspension&nbsp;<\/p>\n\n\n\n<p><strong>Indications<\/strong>:<\/p>\n\n\n\n<p>Oral candidiasis&nbsp;<\/p>\n\n\n\n<p><strong>Dosage<\/strong>:<\/p>\n\n\n\n<p>1 mL (100 mg) rinse and hold in the mouth for as long as possible, q.i.d., p.c., and h.s. for 2 weeks<\/p>\n\n\n\n<p><strong>Side effects\/Adverse Reactions<\/strong>:<\/p>\n\n\n\n<p>Rash, gastrointestinal symptoms&nbsp;<\/p>\n\n\n\n<p><strong>Drug interactions<\/strong>:<\/p>\n\n\n\n<p>No significant drug interactions&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here the Antifungal Medications Used in Dentistry with trade names, indications, dosage, side-effects &amp; drug interactions Nystatin\u00a0 Trade Name: Mycostatin pastilles Mycostatin oral suspension&nbsp; Indications: Oral candidiasis&nbsp; Dosage: One or two pastilles (200,000-400,000 units) dissolved slowly in the mouth 4 to 5 times daily for 10 to 14 days&nbsp; Side effects\/Adverse Reactions: This Antifungal medications<\/p>\n","protected":false},"author":1,"featured_media":664,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ub_ctt_via":""},"categories":[45,52],"tags":[129,74],"featured_image_src":"https:\/\/medinaz.com\/blog\/wp-content\/uploads\/2022\/06\/Antifungal-medications.001.jpeg","author_info":{"display_name":"Medinaz Academy","author_link":"https:\/\/medinaz.com\/blog\/author\/medinaz-blog-admin\/"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.4 - 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