Tinea Versicolor USMLE Notes & Mnemonics contains all the high-yield points you need to know.
- Pityriasis Versicolor: A common fungal skin infection caused by the yeast Malassezia spp., characterized by hypo- or hyperpigmented, scaly patches.
 
Epidemiology:
- More common in warm, humid environments. (Ref)
 - Frequently affects adolescents and young adults.
 
Pathophysiology:
- Overgrowth of the Malassezia yeast on the skin, disrupting normal pigmentation.
 
Clinical Features of Tinea Versicolor (Pityriasis Versicolor):
- Patches on Skin: Often on the trunk and upper arms.
 - Hypo- or Hyperpigmented: Varies with skin tone and sun exposure.
 - Fine Scale: Noted on the surface of the lesions.
 - Asymptomatic: Rarely itchy or symptomatic.
 - Recurrence: Common, especially in warm, humid conditions.
 
Diagnosis:
- Clinical Appearance: Characteristic look of lesions.
 - Wood’s Lamp Examination: Shows yellow-green fluorescence.
 - KOH (Potassium Hydroxide) Prep: “Spaghetti and meatballs” appearance under the microscope.
 
Treatment:
- Topical Antifungals: Selenium sulfide, ketoconazole, or zinc pyrithione shampoos; terbinafine, clotrimazole, or miconazole creams.
 - Systemic Antifungals: Itraconazole or fluconazole for extensive or recurrent cases.
 
Prevention:
- Avoiding excessive sweating, tight clothing.
 - Regular use of antifungal shampoos in endemic areas.
 
Mnemonic: “PITY Versicolor”
- Patches (hypo- or hyperpigmented)
 - Itchy (rarely)
 - Trunk and upper arms
 - Yeast (Malassezia)
 - Various colors
 - Environmental (warm, humid)
 - Recurrent
 - Scale (fine)
 - Identification (Wood’s lamp, KOH prep)
 - Control (antifungals)
 - Overgrowth of yeast
 - Lesions (distinct)
 
Chart: Pityriasis Versicolor Diagnosis and Treatment
| Diagnostic Tool | Finding | Treatment Option | 
|---|---|---|
| Clinical Appearance | Hypo-/hyperpigmented patches | Topical Antifungals | 
| Wood’s Lamp Examination | Yellow-green fluorescence | |
| KOH Prep | “Spaghetti and meatballs” appearance | Systemic Antifungals (for extensive cases) | 
Note: For the USMLE, focus on recognizing the clinical appearance of Pityriasis Versicolor, its association with Malassezia, and the treatment options. The condition is benign but can be a cosmetic concern for patients, and its recurrence is common. Understanding the “spaghetti and meatballs” appearance on KOH prep can be a key test point.
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