Medulloblastoma Brain Tumor Highyield Notes for USMLE, NEET PG, FMGE and Board Exams Medulloblastomas are the most common malignant brain…
This highyield illustrated notes is about Bacterial causes of Diarrhea 1. Bacillus cereus associated diarrhea Diarrhea – watery and non-bloodyAbdominal…
Osteogenesis imperfecta also called “Brittle Bone Disease” comprises a heterogeneous group of heritable disorders. The disorders are frequently associated with blue sclerae, dental abnormalities (dentinogenesis imperfecta), progressive hearing loss, and a positive family history.
Most patients have mutations in one of the two genes coding for Type I collagen
More than 90% of cases exhibit an autosomal dominant inheritance
Commonly mutated genes are COL1A1 and COL1A2
This condition represents one of the most common heritable bone diseases, with a worldwide prevalence of approximately 6 to 7 per 100,000 population.